Efficient synthesis of N-substituted 1,3-thiazin-2-ones containing sulfonamide
نویسندگان
چکیده
Thiazinones containing sulfonamides are experiencing increased interest due to their importance in the design and development of new molecules potential pharmaceutical interest. The synthesis a series Nsubstituted 2H-1,3-thiazin-2-ones sulfonamide is described. compounds were synthesized good yields one-pot reaction starting from commercially available chlorosulfonyl isocyanate (CSI), 3chloro-1-propanethiol, various primary secondary aliphatic, aromatic or heteroaromatic amines. structure one these was established by X-ray crystallography. being evaluated for biological activity.
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ژورنال
عنوان ژورنال: Arkivoc
سال: 2021
ISSN: ['1551-7012', '1551-7004']
DOI: https://doi.org/10.24820/ark.5550190.p011.528